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tnbc
5 items with this tag.
Jul 17, 2026
ZNF689 loss impairs homologous recombination sensitizing triple-negative breast cancer to combined PARP and PD-L1 inhibition
group-study
tnbc
znf689
homologous-recombination
parp-inhibitor
pd-l1
Jul 15, 2026
Extracellular matrix rigidity controls breast cancer metastasis via TYK2-mediated mechanotransduction
group-study
breast-cancer
tnbc
mechanotransduction
tyk2
metastasis
Jul 15, 2026
FGFR3-induced Y158 PARP1 phosphorylation promotes PARP inhibitor resistance via BRG1/MRE11-mediated DNA repair in breast cancer models
group-study
breast-cancer
tnbc
parp-inhibitor
resistance
Jul 15, 2026
Combine mitochondrial-targeted gene therapy and chemotherapy to treat triple-negative breast cancer
group-study
tnbc
mitochondria
gene-therapy
parp-inhibitor
preclinical
Jul 15, 2026
Cisplatin with veliparib or placebo in metastatic triple-negative breast cancer and/or BRCA mutation-associated breast cancer (S1416): a randomised, phase 2 trial
group-study
tnbc
metastatic-breast-cancer
parp-inhibitor
cisplatin
randomized-trial